rs1057519824, MET

N. diseases: 10
Disease: Malignant neoplasm of oropharynx ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Malignant neoplasm of oropharynx
CUI: C0153382
Disease: Malignant neoplasm of oropharynx
0.010 GeneticVariation BEFREE Our results provide evidence that the Met-activating mutation Y1253D is present in a notable subset of patients with oropharyngeal cancer and indicate that it may interfere with radioresponsiveness of these tumours, supporting the notion of aberrant Met signalling as a potential target for radiosensitization. 14627992 2003