rs1061170, CFH

N. diseases: 72
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Myocardial Infarction
CUI: C0027051
Disease: Myocardial Infarction
0.030 GeneticVariation BEFREE The common Y402H variant in complement factor H gene is not associated with susceptibility to myocardial infarction and its related risk factors. 17472578 2007
Myocardial Infarction
CUI: C0027051
Disease: Myocardial Infarction
0.030 GeneticVariation BEFREE Cox proportional hazards analysis was used to determine risk of myocardial infarction for Tyr402His genotypes. 16630992 2006
Myocardial Infarction
CUI: C0027051
Disease: Myocardial Infarction
0.030 GeneticVariation BEFREE In contrast to expected results, we found no association of Y402H polymorphism with risk of atherothrombosis (adjusted: myocardial infarction, OR=1.09, 95%CI 0.88-1.36, p=0.43; ischaemic stroke, OR=1.11, 95%CI 0.81-1.54, p=0.52; venous thromboembolism, OR=1.41, 95%CI 0.88-2.24, p=0.15), nor with baseline plasma C-reactive protein levels [median (interquartile range) mg/L: YY, 1.39 (0.70-2.60); YH, 1.10 (0.57-2.16); HH, 1.00 (0.48-1.79); p=0.14]. 16229850 2006