rs10811661, None

N. diseases: 22
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Gestational Diabetes
CUI: C0085207
Disease: Gestational Diabetes
0.060 GeneticVariation BEFREE The results of this study indicate that the use of 8 genetic polymorphisms associated with carbohydrate and lipid metabolism and type 2 diabetes [<i>PTGS2</i> (<i>COX2</i>) rs6681231, <i>FADS1</i> rs174550, <i>HNF1B</i> rs4430796, <i>ADIPOQ</i> rs266729, <i>IL18</i> rs187238, <i>CCL2</i> rs1024611, <i>HHEX</i> rs5015480 and <i>CDKN2A/2B</i> rs10811661] together with clinical risk factors (BMI and age) may significantly improve the prediction of GDM. 31299695 2019
Gestational Diabetes
CUI: C0085207
Disease: Gestational Diabetes
0.060 GeneticVariation BEFREE In conclusion, the CDKN2A rs10811661 and rs564398 polymorphisms showed association with a greater risk of HBV-related GDM in a Chinese population. 29498096 2018
Gestational Diabetes
CUI: C0085207
Disease: Gestational Diabetes
0.060 GeneticVariation BEFREE GCKR rs780094 and CDKN2A/B rs10811661 polymorphisms were moderately associated with GDM risk. 30074065 2018
Gestational Diabetes
CUI: C0085207
Disease: Gestational Diabetes
0.060 GeneticVariation BEFREE The results of this study suggest an association between CDKN2A/2B gene rs10811661 polymorphism and GDM. 28079868 2017
Gestational Diabetes
CUI: C0085207
Disease: Gestational Diabetes
0.060 GeneticVariation BEFREE Of 45 SNPs, three genetic variants were nominally associated with the development of GDM: rs266729 (p = 0.013, odds ratio [OR]: 1.56, 95% confidence interval [CI]: 1.10-2.23) in ADIPOQ, rs10811661 (p = 0.035, OR: 1.46, 95% CI: 1.03-2.08) in CDKN2A/2B, and rs9505118 (p = 0.046, OR: 1.41, 95% CI: 1.01-1.97) in SSR1-RREB1. 28202837 2017
Gestational Diabetes
CUI: C0085207
Disease: Gestational Diabetes
0.060 GeneticVariation BEFREE Compared with controls (men and women combined), GDM was associated with rs7756992 and rs7754840 (OR 1.55, 95% CI 1.34-1.79, p = 4.17 x 10(-9)) in CDKAL1; rs10811661 (OR 1.49, 95% CI 1.29-1.72, p = 1.05 x 10(-7)) in the CDKN2A-CDKN2B region; rs1111875 (OR 1.27, 95% CI 1.09-1.49, p = 0.003), rs5015480, and rs7923837 in HHEX; rs4402960 (OR 1.18, 95% CI 1.01-1.38, p = 0.03) in IGF2BP2; rs13266634 (OR 1.24, 95% CI 1.07-1.43, p = 0.005) in SLC30A8; and rs7903146 (OR 1.58, 95% CI 1.03-2.43, p = 0.038) in TCF7L2. 19002430 2009