A case-control study was performed to investigate the associations of SNPs in IL-23R gene (rs10889677 and rs1884444) with susceptibility to SLE in 521 Chinese SLE patients and 527 normal controls.
There were no significant differences in the genotype and allele frequencies of rs10889677, rs1884444, and rs7517847 polymorphisms between the patients with SLE and the control group in a Chinese population (for rs10889677: odds ratio [OR] = 1.00, 95% confidence interval [CI] = 0.69-1.45; for rs1884444: OR = 0.96, 95% CI = 0.69-1.33; and for rs7517847: OR = 0.93, 95% CI = 0.67-1.27).