rs10936599, MYNN

N. diseases: 32
Disease: Conventional (Clear Cell) Renal Cell Carcinoma ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Conventional (Clear Cell) Renal Cell Carcinoma
CUI: C0279702
Disease: Conventional (Clear Cell) Renal Cell Carcinoma
0.020 GeneticVariation BEFREE Rs35073794, rs10936599 and rs10069690 were positively correlated with the age older than 55 (OR= 3.27, 95%CI= 1.08-9.93, <i>p</i>=0.031; OR= 1.56, 95%CI= 1.03-2.37, <i>p=</i> 0.034; OR= 4.94, 95%CI= 1.18-20.70, <i>p=</i> 0.022, respectively) with or without history of drinking(OR= 4.47, 95%CI= 0.99-20.25, <i>p=</i> 0.024<i>;</i> OR= 2.62, 95%CI= 1.13-6.08, <i>p=</i> 0.022<i>;</i> OR=2.44, 95%CI=1.03-5.78, <i>p</i>= 0.04, respectively) and clinical stage I/II RCC (OR=2.62, 95%CI=1.02-6.74, <i>p</i>= 0.045; OR= 2.23, 95%CI= 1.08-4.60, <i>p=</i> 0.028; OR= 1.63, 95%CI= 1.17-2.27, <i>p</i>= 0.014, respectively). 29100352 2017
Conventional (Clear Cell) Renal Cell Carcinoma
CUI: C0279702
Disease: Conventional (Clear Cell) Renal Cell Carcinoma
0.020 GeneticVariation BEFREE As a sensitivity analysis, we excluded two telomere length variants in linkage disequilibrium (R<sup>2</sup>>0.5) with GWAS-identified RCC risk variants (rs10936599 and rs9420907) from the telomere length GRS; despite this exclusion, a statistically significant association between the GRS and RCC risk persisted (OR=1.73, 95% CI=1.36-2.21, p<0.0001). 28797570 2017