|
Hypertensive disease
|
|
0.780 |
GeneticVariation
|
GWASCAT |
Interethnic analyses of blood pressure loci in populations of East Asian and European descent.
|
30487518 |
2018 |
|
Hypertensive disease
|
|
0.780 |
GeneticVariation
|
BEFREE |
Associations of the hypertension-related single nucleotide polymorphism rs11191548 with high-density lipoprotein cholesterol and leptin in Chinese children.
|
29338791 |
2018 |
|
Hypertensive disease
|
|
0.780 |
GeneticVariation
|
BEFREE |
In conclusion, the rs11191548 CYP17A1 gene mutation was associated with hypertension and the serum 25(OH) D levels in Han Chinese.
|
29556032 |
2018 |
|
Hypertensive disease
|
|
0.780 |
GeneticVariation
|
BEFREE |
RESULTS The polymorphisms rs11191548 and rs4919687 were significantly associated with hypertension risk, which was confirmed by systolic and diastolic blood pressure distribution analyses between different genotype groups, and these two polymorphisms were found in linkage disequilibrium.
|
28537227 |
2017 |
|
Hypertensive disease
|
|
0.780 |
GeneticVariation
|
BEFREE |
The CYP17A1 polymorphism rs11191548 demonstrated a significant association with LVMI in patients with arterial hypertension and preserved LVEF.
|
26263970 |
2015 |
|
Hypertensive disease
|
|
0.780 |
GeneticVariation
|
BEFREE |
The present meta-analysis indicated significant associations of both CYP17A1 rs11191548 and FGF5 rs16998073 polymorphisms with hypertension susceptibility in East Asians.
|
22959498 |
2013 |
|
Hypertensive disease
|
|
0.780 |
GeneticVariation
|
BEFREE |
Conclusions The SNP rs11191548, near the CYP17A1 gene, was associated with hypertension and SBP in a Chinese Han population.
|
23467202 |
2013 |
|
Hypertensive disease
|
|
0.780 |
GeneticVariation
|
BEFREE |
We investigated the association of rs11191548 with hypertension in Chinese children.
|
22048715 |
2012 |
|
Hypertensive disease
|
|
0.780 |
GeneticVariation
|
BEFREE |
The genetic risk score, calculated as the sum of BP-increasing alleles of FGF5-rs16998073, CYP17A1-rs11191548, CYP17A1-rs1004467 and MTHFR-rs17367504, was significantly associated with increased SBP (1.16 mmHg/allele, P = 9.01E-5), DBP (0.51 mmHg/allele, P = 4.40E-4) and hypertension risk (OR = 1.22/allele, P = 2.74E-7).
|
20852445 |
2011 |
|
Systolic Pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.
|
29455858 |
2018 |
|
Mean blood pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Interethnic analyses of blood pressure loci in populations of East Asian and European descent.
|
30487518 |
2018 |
|
Systolic Pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Interethnic analyses of blood pressure loci in populations of East Asian and European descent.
|
30487518 |
2018 |
|
Diastolic blood pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.
|
29455858 |
2018 |
|
Systolic Pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.
|
28739976 |
2017 |
|
Diastolic blood pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.
|
28739976 |
2017 |
|
Systolic Pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.
|
27618447 |
2016 |
|
Systolic Pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
|
26390057 |
2015 |
|
Coronary heart disease
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
|
21347282 |
2011 |
|
Blood Pressure
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
|
21909110 |
2011 |
|
Systolic Pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.
|
21572416 |
2011 |
|
Systolic blood pressure measurement
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
|
21909115 |
2011 |
|
Systolic Pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
|
21909115 |
2011 |
|
Diastolic blood pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.
|
21572416 |
2011 |
|
Blood Pressure
|
|
0.700 |
GeneticVariation
|
GWASDB |
Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.
|
21572416 |
2011 |
|
Blood Pressure
|
|
0.700 |
GeneticVariation
|
GWASDB |
Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study.
|
21378095 |
2011 |