rs112445441, KRAS

N. diseases: 17
Source: ALL
Disease Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Hematologic Neoplasms
CUI: C0376545
Disease: Hematologic Neoplasms
0.010 GeneticVariation BEFREE We show here that the salient features of ALPS as well as a predisposition to hematological malignancies can be caused by a heterozygous germline Gly13Asp activating mutation of the NRAS oncogene that does not impair CD95-mediated apoptosis. 17517660 2007