Disease: Carcinoma, Basal Cell ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Carcinoma, Basal Cell
CUI: C4721806
Disease: Carcinoma, Basal Cell
0.020 GeneticVariation BEFREE We genotyped a frequent TYR variant (p.R402Q) in 1273 patients {1047 cutaneous melanoma (CM) and 226 basal cell carcinoma (BCC)} and 925 controls, and the full coding region of TYR was sequenced in 287 patients suspected of genetic predisposition to SK (familial and/or multiple SK and/or onset before 40 years) and 187 controls. 21906913 2011
Carcinoma, Basal Cell
CUI: C4721806
Disease: Carcinoma, Basal Cell
0.020 GeneticVariation BEFREE The variant in TYR encoding the R402Q amino acid substitution, previously shown to affect eye color and tanning response, conferred risk of CM (OR = 1.21, P = 2.8 x 10(-7)) and BCC (OR = 1.14, P = 6.1 x 10(-4)). 18488027 2008