|
melanoma
|
|
0.730 |
GeneticVariation
|
GWASDB |
Identification of a melanoma susceptibility locus and somatic mutation in TET2.
|
24980573 |
2014 |
|
melanoma
|
|
0.730 |
GeneticVariation
|
BEFREE |
The association with melanoma of the TYR variant p.Arg402Gln was also statistically significant (OR: 1.50; 95% CI: 1.11-2.04; p-value=0.0089).
|
22464347 |
2012 |
|
melanoma
|
|
0.730 |
GeneticVariation
|
BEFREE |
The homozygous p.R402Q variant was significantly associated with SK risk (P value=0.008; OR=1.57), and was mostly associated with multiple CM risk (P value=0.021; OR=2.50) and familial CM risk (P value=0.022; OR=2.16).
|
21906913 |
2011 |
|
melanoma
|
|
0.730 |
GeneticVariation
|
BEFREE |
The variant in TYR encoding the R402Q amino acid substitution, previously shown to affect eye color and tanning response, conferred risk of CM (OR = 1.21, P = 2.8 x 10(-7)) and BCC (OR = 1.14, P = 6.1 x 10(-4)).
|
18488027 |
2008 |
|
Squamous cell carcinoma
|
|
0.710 |
GeneticVariation
|
GWASCAT |
Combined analysis of keratinocyte cancers identifies novel genome-wide loci.
|
31174203 |
2019 |
|
Squamous cell carcinoma
|
|
0.710 |
GeneticVariation
|
GWASCAT |
Identification of Susceptibility Loci for Cutaneous Squamous Cell Carcinoma.
|
26829030 |
2016 |
|
Albinism
|
|
0.710 |
GeneticVariation
|
BEFREE |
Finally, we review the TYR p.R402Q temperature-sensitive variant and confirm its association with cases of albinism with only one identifiable TYR mutation.
|
23504663 |
2013 |
|
Squamous cell carcinoma
|
|
0.710 |
GeneticVariation
|
BEFREE |
The TYR haplotype carrying only the Arg402Gln variant allele was significantly associated with SCC risk (OR, 1.35; 95% CI, 1.04-1.74).
|
19384953 |
2009 |
|
Albinism
|
|
0.710 |
GeneticVariation
|
CLINVAR |
|
|
|
|
Basal Cell Cancer
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Combined analysis of keratinocyte cancers identifies novel genome-wide loci.
|
31174203 |
2019 |
|
Basal Cell Neoplasm
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Combined analysis of keratinocyte cancers identifies novel genome-wide loci.
|
31174203 |
2019 |
|
Basal cell carcinoma
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Combined analysis of keratinocyte cancers identifies novel genome-wide loci.
|
31174203 |
2019 |
|
Suntan
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure.
|
29739929 |
2018 |
|
Skin Pigmentation
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort.
|
30166351 |
2018 |
|
Vitiligo
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants.
|
27723757 |
2016 |
|
Squamous cell carcinoma of skin
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association study identifies novel susceptibility loci for cutaneous squamous cell carcinoma.
|
27424798 |
2016 |
|
Basal Cell Neoplasm
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma.
|
27539887 |
2016 |
|
Basal Cell Cancer
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma.
|
27539887 |
2016 |
|
Basal cell carcinoma
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma.
|
27539887 |
2016 |
|
Suntan
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.
|
23548203 |
2013 |
|
ALBINISM, OCULOCUTANEOUS, TYPE IB (disorder)
|
|
0.700 |
CausalMutation
|
CLINVAR |
|
|
|
|
Elevated hepatic transaminase
|
|
0.700 |
GeneticVariation
|
CLINVAR |
|
|
|
|
ALBINISM, OCULOCUTANEOUS, TYPE I, TEMPERATURE-SENSITIVE
|
|
0.700 |
CausalMutation
|
CLINVAR |
|
|
|
|
Abnormality of metabolism/homeostasis
|
|
0.700 |
GeneticVariation
|
CLINVAR |
|
|
|
|
SKIN/HAIR/EYE PIGMENTATION 3, BLUE/GREEN EYES
|
|
0.700 |
GeneticVariation
|
CLINVAR |
|
|
|