rs1127354, ITPA

N. diseases: 26
Disease: Anemia, severe ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Anemia, severe
CUI: C0238644
Disease: Anemia, severe
0.020 GeneticVariation BEFREE However, ITPA polymorphism (rs1127354) is useful for predicting the development of severe anemia and will be helpful in the management of treatment. 23707372 2013
Anemia, severe
CUI: C0238644
Disease: Anemia, severe
0.020 GeneticVariation BEFREE The increased tolerability to RTP concentrations in erythrocytes in the ITPA variant rs1127354 plays a role in preventing RBV-induced severe anemia in this ITPA variant. 30817703 2019