rs1127354, ITPA

N. diseases: 26
Disease: Anemia, severe ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Anemia, severe
CUI: C0238644
Disease: Anemia, severe
0.020 GeneticVariation BEFREE The increased tolerability to RTP concentrations in erythrocytes in the ITPA variant rs1127354 plays a role in preventing RBV-induced severe anemia in this ITPA variant. 30817703 2019
Anemia, severe
CUI: C0238644
Disease: Anemia, severe
0.020 GeneticVariation BEFREE However, ITPA polymorphism (rs1127354) is useful for predicting the development of severe anemia and will be helpful in the management of treatment. 23707372 2013