rs1131691014, TP53

N. diseases: 214
Disease: Childhood Osteosarcoma ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Childhood Osteosarcoma
CUI: C1332986
Disease: Childhood Osteosarcoma
0.020 GeneticVariation BEFREE The study provides evidence supporting the association of MDM2 SNP309 with high-grade osteosarcoma risk in females and shows that TP53 Arg72Pro has a prognostic value for overall survival and EFS in osteosarcoma patients. 19451596 2009
Childhood Osteosarcoma
CUI: C1332986
Disease: Childhood Osteosarcoma
0.020 GeneticVariation BEFREE These data do not indicate a strong link between variation in TP53 and OS risk, although they provide preliminary evidence of an increased risk of OS associated with variants at IVS2+38 and Pro72Arg. 17096406 2007