rs113488022, BRAF

N. diseases: 490
Disease: Colorectal Neoplasms ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Colorectal Neoplasms
CUI: C0009404
Disease: Colorectal Neoplasms
0.790 CausalMutation CLINVAR KRAS, BRAF, PIK3CA, and PTEN mutations: implications for targeted therapies in metastatic colorectal cancer. 21163703 2011
Colorectal Neoplasms
CUI: C0009404
Disease: Colorectal Neoplasms
0.790 CausalMutation CLINVAR Prognostic vs predictive molecular biomarkers in colorectal cancer: is KRAS and BRAF wild type status required for anti-EGFR therapy? 21129611 2010
Colorectal Neoplasms
CUI: C0009404
Disease: Colorectal Neoplasms
0.790 CausalMutation CLINVAR Vemurafenib synergizes with nutlin-3 to deplete survivin and suppresses melanoma viability and tumor growth. 23812671 2013
Colorectal Neoplasms
CUI: C0009404
Disease: Colorectal Neoplasms
0.790 CausalMutation CLINVAR Clinical biomarkers in oncology: focus on colorectal cancer. 19537845 2009
Colorectal Neoplasms
CUI: C0009404
Disease: Colorectal Neoplasms
0.790 CausalMutation CLINVAR Our findings indicated that proteasome inhibition might represent a valuable targeting strategy in BRAF V600E-mutant colorectal tumors. 24107445 2013
Colorectal Neoplasms
CUI: C0009404
Disease: Colorectal Neoplasms
0.790 CausalMutation CLINVAR BRAF V600E mutation and resistance to anti-EGFR monoclonal antibodies in patients with metastatic colorectal cancer: a meta-analysis. 20857202 2011
Colorectal Neoplasms
CUI: C0009404
Disease: Colorectal Neoplasms
0.790 CausalMutation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Colorectal Neoplasms
CUI: C0009404
Disease: Colorectal Neoplasms
0.790 CausalMutation CLINVAR Massively parallel tumor multigene sequencing to evaluate response to panitumumab in a randomized phase III study of metastatic colorectal cancer. 23325582 2013