rs113488022, BRAF

N. diseases: 490
Disease: ovarian neoplasm ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 GeneticVariation BEFREE Sustained response to vemurafenib in a low grade serous ovarian cancer with a BRAF V600E mutation. 26490654 2015
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 GeneticVariation BEFREE In this study, we compared detection of the V600E mutation in serous ovarian tumors by VE1 immunostaining and by allele-specific polymerase chain reaction. 23089489 2013
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 GeneticVariation BEFREE The presence of the BRAF V600E mutation in SB/LGS ovarian cancer was associated with early stage disease and improved prognosis. 22930283 2013
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 GeneticVariation BEFREE No BRAF V600E mutations were detected in nonserous epithelial ovarian tumors. 22820660 2013
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 CausalMutation CLINVAR Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial. 22608338 2012
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 CausalMutation CLINVAR Improved survival with vemurafenib in melanoma with BRAF V600E mutation. 21639808 2011
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 CausalMutation CLINVAR Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer--shifting the paradigm. 21683865 2011
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 CausalMutation CLINVAR Epidermal growth factor receptor blockers for the treatment of ovarian cancer. 21975775 2011
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 GeneticVariation BEFREE One recurrent somatic mutation, p.V600E, is frequently found in several tumor types, such as melanoma, papillary thyroid carcinoma, colon cancer, and ovarian cancer. 20735442 2011
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 CausalMutation CLINVAR Inhibition of mutated, activated BRAF in metastatic melanoma. 20818844 2010
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 CausalMutation CLINVAR KRAS or BRAF mutation status is a useful predictor of sensitivity to MEK inhibition in ovarian cancer. 19018267 2008
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.750 CausalMutation CLINVAR Mutations of the BRAF gene in human cancer. 12068308 2002