rs1137101, LEPR

N. diseases: 77
Disease: Impaired glucose tolerance ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Impaired glucose tolerance
CUI: C0271650
Disease: Impaired glucose tolerance
0.020 GeneticVariation BEFREE Two polymorphisms (Lys109Arg, Gln223Arg) in the extracellular domain of the leptin receptor predicted the conversion to type 2 diabetes in high-risk individuals with IGT. 15997246 2005
Impaired glucose tolerance
CUI: C0271650
Disease: Impaired glucose tolerance
0.020 GeneticVariation BEFREE In postmenopausal women with IGT (n = 24), associations were found with Lys(109)Arg and Lys(656)Asn for fasting insulin (P = 0.05) and with Lys(109)Arg and Gln(223)Arg for the insulin response to an OGTT (P < 0.02). 11443193 2001