rs1137101, LEPR

N. diseases: 77
Disease: Hypertensive disease ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.040 GeneticVariation BEFREE The aim of the present study was to evaluate four single nucleotide polymorphisms (SNPs) of APLNR genes (rs11544374 and rs948847), LEPR (rs1137101) and leptin (rs7799039) gene in patients with CAD and hypertension. 29883719 2018
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.040 GeneticVariation BEFREE Overall and subgroup analyses failed to reveal any significance for the association between the Gln223Arg polymorphism and hypertension risk. 25475696 2015
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.040 GeneticVariation BEFREE Our results suggest that the Gln223Arg polymorphism of the leptin receptor is significantly associated with plasma leptin levels and left ventricular hypertrophy in hypertension. 24485307 2013
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.040 GeneticVariation BEFREE This case-control study showed associations between the frequencies of AA genotype and A allele of Gln223Arg and hypertension</span> (p=0.029, p=0.002, respectively). 22293279 2012