rs1137101, LEPR

N. diseases: 77
Disease: Psychotic Disorders ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Psychotic Disorders
CUI: C0033975
Disease: Psychotic Disorders
0.020 GeneticVariation BEFREE To determine whether genetic polymorphisms related to pharmacodynamics with metabolic adverse effects, namely leptin promoter (<i>LEP</i>) rs7799039, leptin receptor rs1137101, dopamine D2 rs4436578, serotonin 5-HT2A rs6313, and serotonin 5-HT2C rs518147 and rs12836771, are associated with hyperglycemia induced by risperidone or clozapine in adult Thai patients with psychosis. 31496784 2019
Psychotic Disorders
CUI: C0033975
Disease: Psychotic Disorders
0.020 GeneticVariation BEFREE The LEPR Q223R polymorphism may be a risk factor for obesity in women with a psychotic disorder treated with atypical antipsychotic drugs. 21510767 2011