rs11556924, ZC3HC1

N. diseases: 21
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Arteriosclerosis
CUI: C0003850
Disease: Arteriosclerosis
0.030 GeneticVariation BEFREE In the present study, we aimed to examine the role of two single-nucleotide polymorphisms (SNPs), rs3825807 and rs11556924, located in the ADAMTS7 and ZC3HC1 genes, respectively, associated with CAD in published GWASs in European populations and their possible contribution to the development of coronary atherosclerosis and cerebral LA atherosclerosis in a case-control study of an the Iranian population. 31679296 2019
Arteriosclerosis
CUI: C0003850
Disease: Arteriosclerosis
0.030 GeneticVariation BEFREE The resulting amino acid change Arg363His is associated with increased expression and nuclear mobility, as well as lower rates of cell growth in HeLa cells, further supporting a role for cell proliferation in atherosclerosis and its clinical consequences. 28115489 2017
Arteriosclerosis
CUI: C0003850
Disease: Arteriosclerosis
0.030 GeneticVariation BEFREE Our results indicate that ZC3HC1 rs11556924 polymorphism is associated with subclinical atherosclerosis in RA. 24286297 2013