rs11591147, PCSK9

N. diseases: 28
Disease: Neural Tube Defects ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Neural Tube Defects
CUI: C0027794
Disease: Neural Tube Defects
0.010 GeneticVariation BEFREE The R46L variant was also associated with an increased risk of spina bifida (OR 5.90, p = 2.7 × 10<sup>-4</sup>), suggesting that further investigation of potential connections between inhibition of PCSK9 and neural tube defects may be warranted. 29185237 2018