rs11615, ERCC1

N. diseases: 62
Disease: Carcinoma of larynx ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Carcinoma of larynx
CUI: C0595989
Disease: Carcinoma of larynx
0.020 GeneticVariation BEFREE By stratified analysis, ERCC1 rs11615 CC genotype and C allele were significantly associated with greatly increased risk of laryngeal cancer in ever smokers. 24563277 2014
Carcinoma of larynx
CUI: C0595989
Disease: Carcinoma of larynx
0.020 GeneticVariation BEFREE In conclusion, our study suggests that ERCC1 rs11615 and ERCC5 rs17655 polymorphisms are associated with increased risk of laryngeal cancer, and that they confer more risk among smokers and drinkers. 24582975 2014