Osteosarcoma of bone
|
|
0.100 |
GeneticVariation
|
BEFREE |
In addition, no evidence of association was observed between prognosis in osteosarcoma and <i>ERCC1</i> rs11615, <i>ERCC1</i> rs3212986, <i>ERCC1</i> rs2298881, <i>ERCC2</i> rs13181, <i>ERCC4</i> rs1800067, and <i>ERCC5</i> rs1047768 polymorphisms.
|
29950854 |
2018 |
Childhood Osteosarcoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
The ERCC2-rs1799793 AA+AC > CC (OR=1.3428, 95% CI=1.0201; 1.7674) had an effect on the risk of osteosarcoma development, whereas, there were no significant associations among the other ERCC SNPs (ERCC1 rs3212986, ERCC1 rs11615, and ERCC2 rs13181) and osteosarcoma.
|
30402838 |
2018 |
Osteosarcoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
The ERCC2-rs1799793 AA+AC > CC (OR=1.3428, 95% CI=1.0201; 1.7674) had an effect on the risk of osteosarcoma development, whereas, there were no significant associations among the other ERCC SNPs (ERCC1 rs3212986, ERCC1 rs11615, and ERCC2 rs13181) and osteosarcoma.
|
30402838 |
2018 |
Osteosarcoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
In addition, no evidence of association was observed between prognosis in osteosarcoma and <i>ERCC1</i> rs11615, <i>ERCC1</i> rs3212986, <i>ERCC1</i> rs2298881, <i>ERCC2</i> rs13181, <i>ERCC4</i> rs1800067, and <i>ERCC5</i> rs1047768 polymorphisms.
|
29950854 |
2018 |
Osteosarcoma of bone
|
|
0.100 |
GeneticVariation
|
BEFREE |
The ERCC2-rs1799793 AA+AC > CC (OR=1.3428, 95% CI=1.0201; 1.7674) had an effect on the risk of osteosarcoma development, whereas, there were no significant associations among the other ERCC SNPs (ERCC1 rs3212986, ERCC1 rs11615, and ERCC2 rs13181) and osteosarcoma.
|
30402838 |
2018 |
Childhood Osteosarcoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
In addition, no evidence of association was observed between prognosis in osteosarcoma and <i>ERCC1</i> rs11615, <i>ERCC1</i> rs3212986, <i>ERCC1</i> rs2298881, <i>ERCC2</i> rs13181, <i>ERCC4</i> rs1800067, and <i>ERCC5</i> rs1047768 polymorphisms.
|
29950854 |
2018 |
Osteosarcoma of bone
|
|
0.100 |
GeneticVariation
|
BEFREE |
ERCC1 (C118T (rs11615) and C8092A (rs3212986)) and ERCC2 (A751C (rs171140) and G312A (rs1799793)) polymorphisms were analysed in 44 patients with osteosarcoma, who were treated with cisplatin based neoadjuvant chemotherapy.
|
29980176 |
2018 |
Childhood Osteosarcoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
ERCC1 (C118T (rs11615) and C8092A (rs3212986)) and ERCC2 (A751C (rs171140) and G312A (rs1799793)) polymorphisms were analysed in 44 patients with osteosarcoma, who were treated with cisplatin based neoadjuvant chemotherapy.
|
29980176 |
2018 |
Osteosarcoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
ERCC1 (C118T (rs11615) and C8092A (rs3212986)) and ERCC2 (A751C (rs171140) and G312A (rs1799793)) polymorphisms were analysed in 44 patients with osteosarcoma, who were treated with cisplatin based neoadjuvant chemotherapy.
|
29980176 |
2018 |
Childhood Osteosarcoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Haplotype containing the rs1799793-T and rs11615-T alleles was associated with a statistically increased osteosarcoma risk, OR (95% CI) = 1.47 (1.12-1.92).
|
28474168 |
2017 |
Osteosarcoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Haplotype containing the rs1799793-T and rs11615-T alleles was associated with a statistically increased osteosarcoma risk, OR (95% CI) = 1.47 (1.12-1.92).
|
28474168 |
2017 |
Osteosarcoma of bone
|
|
0.100 |
GeneticVariation
|
BEFREE |
This suggests rs11615 may be a useful genetic marker for predicting osteosarcoma prognosis.
|
28977987 |
2017 |
Osteosarcoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
This suggests rs11615 may be a useful genetic marker for predicting osteosarcoma prognosis.
|
28977987 |
2017 |
Osteosarcoma of bone
|
|
0.100 |
GeneticVariation
|
BEFREE |
Haplotype containing the rs1799793-T and rs11615-T alleles was associated with a statistically increased osteosarcoma risk, OR (95% CI) = 1.47 (1.12-1.92).
|
28474168 |
2017 |
Childhood Osteosarcoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
This suggests rs11615 may be a useful genetic marker for predicting osteosarcoma prognosis.
|
28977987 |
2017 |
Childhood Osteosarcoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
In summary, our results suggested that the ERCC1 rs11615 and rs2298881 polymorphisms play important roles in the response to chemotherapy mediated by the DNA repair pathway and in the clinical outcome of osteosarcoma.
|
26345951 |
2015 |
Osteosarcoma of bone
|
|
0.100 |
GeneticVariation
|
BEFREE |
In summary, our results suggested that the ERCC1 rs11615 and rs2298881 polymorphisms play important roles in the response to chemotherapy mediated by the DNA repair pathway and in the clinical outcome of osteosarcoma.
|
26345951 |
2015 |
Osteosarcoma of bone
|
|
0.100 |
GeneticVariation
|
BEFREE |
In conclusion, our findings suggest that ERCC1 rs11615 and ERCC1 rs2298881 genetic polymorphisms are significantly associated with poor response to chemotherapy and unfavourable survival of osteosarcoma.
|
26339355 |
2015 |
Osteosarcoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
In summary, our results suggested that the ERCC1 rs11615 and rs2298881 polymorphisms play important roles in the response to chemotherapy mediated by the DNA repair pathway and in the clinical outcome of osteosarcoma.
|
26345951 |
2015 |
Osteosarcoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
In conclusion, our results suggest that ERCC1 rs11615 and ERCC2 rs1799793 may be useful genetic prognostic markers for osteosarcoma in a Chinese population.
|
26436406 |
2015 |
Osteosarcoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
In conclusion, our findings suggest that ERCC1 rs11615 and ERCC1 rs2298881 genetic polymorphisms are significantly associated with poor response to chemotherapy and unfavourable survival of osteosarcoma.
|
26339355 |
2015 |
Osteosarcoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
In conclusion, our results suggest that the ERCC1 rs11615 polymorphism might influence the response to cisplatin-based chemotherapy and affect the clinical outcome for osteosarcoma patients.
|
26400354 |
2015 |
Osteosarcoma of bone
|
|
0.100 |
GeneticVariation
|
BEFREE |
In conclusion, our results suggest that ERCC1 rs11615 and ERCC2 rs1799793 may be useful genetic prognostic markers for osteosarcoma in a Chinese population.
|
26436406 |
2015 |
Childhood Osteosarcoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
In conclusion, our results suggest that ERCC1 rs11615 and ERCC2 rs1799793 may be useful genetic prognostic markers for osteosarcoma in a Chinese population.
|
26436406 |
2015 |
Childhood Osteosarcoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
In conclusion, our results suggest that the ERCC1 rs11615 polymorphism might influence the response to cisplatin-based chemotherapy and affect the clinical outcome for osteosarcoma patients.
|
26400354 |
2015 |