|
GALLBLADDER DISEASE 4
|
|
0.700 |
CausalMutation
|
CLINVAR |
|
|
|
|
Cholecystolithiasis
|
|
0.800 |
GeneticVariation
|
BEFREE |
D19H was found to be significantly associated with gallstones (odds ratio [OR] = 2.9, P = 0.0220, 95% confidence interval [CI]:1.22-6.89), particularly in the overweight cohort (OR = 3.2, P = 0.0430, 95% CI:1.07-9.26).
|
23406058 |
2013 |
|
Cholelithiasis
|
|
0.800 |
GeneticVariation
|
BEFREE |
A common genetic polymorphism D19H of ABCG8 associated with gallstone disease may be causatively related to the genetic predisposition of GBC.
|
19018975 |
2009 |
|
Cholecystolithiasis
|
|
0.800 |
GeneticVariation
|
GWASDB |
A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease.
|
17632509 |
2007 |
|
Cholelithiasis
|
|
0.800 |
GeneticVariation
|
GWASDB |
A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease.
|
17632509 |
2007 |
|
Biliary calculi
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease.
|
17632509 |
2007 |
|
Cholelithiasis
|
|
0.800 |
GeneticVariation
|
BEFREE |
ABCG5 rs6756629 is in strong linkage disequilibrium with rs11887534 (D19H), a variant previously associated with gallstone disease risk in populations of European-descent.
|
24256507 |
2013 |
|
Cholecystolithiasis
|
|
0.800 |
GeneticVariation
|
BEFREE |
ABCG8-D19H is a predictor of gallstone recurrence, a major long term postoperative biliary complication.
|
22869156 |
2013 |
|
Cholelithiasis
|
|
0.800 |
GeneticVariation
|
BEFREE |
ABCG8-D19H is a predictor of gallstone recurrence, a major long term postoperative biliary complication.
|
22869156 |
2013 |
|
Cholelithiasis
|
|
0.800 |
GeneticVariation
|
BEFREE |
Among individuals of African American and Hispanic American ancestry, rs11887534 and rs4245791 were associated positively with gallstone disease risk, whereas the association for the rs1260326 variant was inverse.
|
27094239 |
2016 |
|
Low density lipoprotein cholesterol measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
|
27286809 |
2016 |
|
C-reactive protein measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
|
27286809 |
2016 |
|
Cholelithiasis
|
|
0.800 |
GeneticVariation
|
BEFREE |
Both gallstone disease and p.D19H of ABCG8 are associated with diminished cholesterol absorption.
|
23406058 |
2013 |
|
Cholelithiasis
|
|
0.800 |
GeneticVariation
|
BEFREE |
Carriers of ABCG5 604Q or ABCG8 D19H polymorphisms have an increased risk of gallstone disease independent of age, sex and body mass index.
|
18457353 |
2008 |
|
Cholelithiasis
|
|
0.800 |
GeneticVariation
|
BEFREE |
Carriers of the CG genotype of ABCG8 rs118</span>87534 had higher risk of bi</span>liary stones [odds ratio (OR) = 2.3, 95% confidence interval (CI) 0.82-6.5), gallbladder cancer (OR = 4.3, 95% CI 1.7-10.4) and bile duct cancer (OR = 1.94, 95% CI 0.64-5.91), compared with carriers of the GG genotype.
|
21062971 |
2011 |
|
Gallbladder Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Carriers of the CG genotype of ABCG8 rs11887534 had higher risk of biliary stones [odds ratio (OR) = 2.3, 95% confidence interval (CI) 0.82-6.5), gallbladder cancer (OR = 4.3, 95% CI 1.7-10.4) and bile duct cancer (OR = 1.94, 95% CI 0.64-5.91), compared with carriers of the GG genotype.
|
21062971 |
2011 |
|
Stage IIB Gallbladder Cancer AJCC v8
|
|
0.020 |
GeneticVariation
|
BEFREE |
Carriers of the CG genotype of ABCG8 rs11887534 had higher risk of biliary stones [odds ratio (OR) = 2.3, 95% confidence interval (CI) 0.82-6.5), gallbladder cancer (OR = 4.3, 95% CI 1.7-10.4) and bile duct cancer (OR = 1.94, 95% CI 0.64-5.91), compared with carriers of the GG genotype.
|
21062971 |
2011 |
|
Stage 0 Gallbladder Cancer AJCC v8
|
|
0.020 |
GeneticVariation
|
BEFREE |
Carriers of the CG genotype of ABCG8 rs11887534 had higher risk of biliary stones [odds ratio (OR) = 2.3, 95% confidence interval (CI) 0.82-6.5), gallbladder cancer (OR = 4.3, 95% CI 1.7-10.4) and bile duct cancer (OR = 1.94, 95% CI 0.64-5.91), compared with carriers of the GG genotype.
|
21062971 |
2011 |
|
Stage IIA Gallbladder Cancer AJCC v8
|
|
0.020 |
GeneticVariation
|
BEFREE |
Carriers of the CG genotype of ABCG8 rs11887534 had higher risk of biliary stones [odds ratio (OR) = 2.3, 95% confidence interval (CI) 0.82-6.5), gallbladder cancer (OR = 4.3, 95% CI 1.7-10.4) and bile duct cancer (OR = 1.94, 95% CI 0.64-5.91), compared with carriers of the GG genotype.
|
21062971 |
2011 |
|
Stage III Gallbladder Cancer AJCC v8
|
|
0.020 |
GeneticVariation
|
BEFREE |
Carriers of the CG genotype of ABCG8 rs11887534 had higher risk of biliary stones [odds ratio (OR) = 2.3, 95% confidence interval (CI) 0.82-6.5), gallbladder cancer (OR = 4.3, 95% CI 1.7-10.4) and bile duct cancer (OR = 1.94, 95% CI 0.64-5.91), compared with carriers of the GG genotype.
|
21062971 |
2011 |
|
Stage IV Gallbladder Cancer AJCC v8
|
|
0.020 |
GeneticVariation
|
BEFREE |
Carriers of the CG genotype of ABCG8 rs11887534 had higher risk of biliary stones [odds ratio (OR) = 2.3, 95% confidence interval (CI) 0.82-6.5), gallbladder cancer (OR = 4.3, 95% CI 1.7-10.4) and bile duct cancer (OR = 1.94, 95% CI 0.64-5.91), compared with carriers of the GG genotype.
|
21062971 |
2011 |
|
Cholangiocarcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Carriers of the CG genotype of ABCG8 rs11887534 had higher risk of biliary stones [odds ratio (OR) = 2.3, 95% confidence interval (CI) 0.82-6.5), gallbladder cancer (OR = 4.3, 95% CI 1.7-10.4) and bile duct cancer (OR = 1.94, 95% CI 0.64-5.91), compared with carriers of the GG genotype.
|
21062971 |
2011 |
|
Bile duct carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Carriers of the CG genotype of ABCG8 rs11887534 had higher risk of biliary stones [odds ratio (OR) = 2.3, 95% confidence interval (CI) 0.82-6.5), gallbladder cancer (OR = 4.3, 95% CI 1.7-10.4) and bile duct cancer (OR = 1.94, 95% CI 0.64-5.91), compared with carriers of the GG genotype.
|
21062971 |
2011 |
|
Malignant neoplasm of gallbladder
|
|
0.020 |
GeneticVariation
|
BEFREE |
Carriers of the CG genotype of ABCG8 rs11887534 had higher risk of biliary stones [odds ratio (OR) = 2.3, 95% confidence interval (CI) 0.82-6.5), gallbladder cancer (OR = 4.3, 95% CI 1.7-10.4) and bile duct cancer (OR = 1.94, 95% CI 0.64-5.91), compared with carriers of the GG genotype.
|
21062971 |
2011 |
|
Cholelithiasis
|
|
0.800 |
GeneticVariation
|
BEFREE |
Carriers of the DH genotype and H allele of the ABCG8 D19H polymorphism harbor a higher risk for gallstone susceptibility in the northern Indian population.
|
21039838 |
2010 |