rs121434568, EGFR

N. diseases: 73
Disease: Mucinous Adenocarcinoma ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Mucinous Adenocarcinoma
CUI: C0007130
Disease: Mucinous Adenocarcinoma
0.010 GeneticVariation BEFREE Here, we show that haploinsufficiency of Nkx2-1 in combination with oncogenic Kras(G12D), but not with oncogenic EGFR(L858R), caused pulmonary tumors in transgenic mice that were phenotypically similar to human mucinous adenocarcinomas. 23143308 2012