|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
Correlation between the 677C>T polymorphism in the methylene tetrahydrofolate reductase gene and serum homocysteine levels in coronary heart disease.
|
27051002 |
2016 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
Methylenetetrahydrofolate reductase C677T polymorphism is associated with increased risk of coronary artery disease in young South African Indians.
|
26095803 |
2015 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
The association of MTHFR C677T gene variants and lipid profiles or body mass index in patients with diabetic and nondiabetic coronary heart disease.
|
24218123 |
2013 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
Methylenetetrahydrofolate reductase C677T gene polymorphism and coronary artery disease in a Chinese Han population: a meta-analysis.
|
22146089 |
2012 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
Role of homocysteine & MTHFR C677T gene polymorphism as risk factors for coronary artery disease in young Indians.
|
22664498 |
2012 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
Detection of C677T mutation of MTHFR in subject with coronary heart disease by hairpin probe with enzymatic color on microarray.
|
21802936 |
2011 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
The C677T polymorphism of 5,10 methylenetetrahydrofolate reductase (MTHFR) gene has been associated with hypertension and coronary artery disease in several populations worldwide, but results are still controversial.
|
20637366 |
2010 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
High plasma homocysteine is associated with the risk of coronary artery disease independent of methylenetetrahydrofolate reductase 677C-->T genotypes.
|
18586656 |
2008 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
The C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with early onset of coronary artery disease in some populations with certain ethnic backgrounds.
|
18751630 |
2008 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
Plasma homocysteine levels & 677C-->T methylenetetrahydrofolate reductase gene polymorphism in patients with coronary artery disease of different severity.
|
18403793 |
2008 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
Dynamic regulation of MTHFR mRNA expression and C677T genotype modulate mortality in coronary artery disease patients after revascularization.
|
17604826 |
2007 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
Sex-specific effect of the thermolabile C677T mutation in the methylenetetrahydrofolate reductase gene on angiographically assessed coronary artery disease in Brazilians.
|
18075008 |
2007 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
Gene--nutrition interactions in coronary artery disease: correlation between the MTHFR C677T polymorphism and folate and homocysteine status in a Korean population.
|
15935452 |
2006 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
C677T mutation of methylenetetrahydrofolate reductase gene and serum homocysteine levels in Turkish patients with coronary artery disease.
|
15648053 |
2006 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
Recent studies have shown that a common mutation (nucleotide 677 C-->T) in the methylenetetrahydrofolate reductase (MTHFR) gene may contribute to a mild rise in plasma homocysteine levels and increase the incidence of coronary artery disease.
|
16489563 |
2006 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
The oxidative modification of low-density lipoprotein (LDL) has been suggested to be a key element in atherogenesis, while methylenetetrahydrofolate reductase (MTHFR) C677T mutation has been associated with the development of coronary heart disease.
|
16487909 |
2006 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
The objective of our study is to evaluate the single locus and combined effects of three different genetic polymorphisms (methylenetetrahydrofolate reductase C677T polymorphism, plasminogen activator inhibitor 4G/5G polymorphism, and endothelial nitric oxide synthase 3-27 base pairs repeat polymorphism) on the presence and extent of coronary artery disease in patients with early-onset coronary artery disease.
|
16845248 |
2006 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
No strong evidence exists to support an association of the MTHFR 677 C-->T polymorphism and coronary heart disease in Europe, North America, or Australia.
|
16216822 |
2005 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
One putative determinant of PAD is the 677C>T polymorphism in the gene encoding methylenetetrahydrofolate reductase (MTHFR), which has previously been found to associate with various diabetic complications including retinopathy, nephropathy, atherosclerosis and coronary heart disease.
|
16274479 |
2005 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
We studied several single nucleotide polymorphisms (SNP) in Hcy-regulating genes [methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C; methionine synthase (MS) A2756G; methionine synthase reductase (MTRR) A66G] in relation to total plasma Hcy levels, transplant coronary artery disease and thromboembolic episodes in 84 heart transplant patients, and we compared the incidence of these polymorphisms with those in a healthy adult controls.
|
15612980 |
2005 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
Factor V G1691A, prothrombin G20210A, and methylenetetrahydrofolate reductase [MTHFR] C677T gene polymorphism in angiographically documented coronary artery disease.
|
15353918 |
2004 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
The 5,10-methylenetetrahydrofolate reductase gene (MTHFR) 677C-->T polymorphism modifies the risk of coronary artery disease and colon cancer and is related to plasma concentrations of total homocysteine (tHcy).
|
15447919 |
2004 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
Prevalence and role of methylenetetrahydrofolate reductase 677 C-->T and 1298 A-->C polymorphisms in coronary artery disease in Arabs.
|
14521457 |
2003 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
We investigated the influence of elevated homocysteine plasma levels and 2 polymorphisms, 677C/T and 1298A/C, of the methylenetetrahydrofolate reductase (MTHFR) gene on the risk of restenosis after stenting in patients with symptomatic coronary artery disease.
|
14604831 |
2003 |
|
Coronary Arteriosclerosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
Methylenetetrahydrofolate reductase gene C677T polymorphism, homocysteine, vitamin B12, and DNA damage in coronary artery disease.
|
12522558 |
2003 |