|
Deep Vein Thrombosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
Relationship between genetic polymorphism of MTHFR C677T and lower extremities deep venous thrombosis.
|
30303041 |
2019 |
|
Deep Vein Thrombosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
Thus, the aim of the present study is to determine the prevalence of FVL, MTHFR C677T and MTHFR A1298C gene polymorphisms in patients with DVT in central Iran.
|
29855758 |
2018 |
|
Deep Vein Thrombosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
GpIIIa 1565T/C and homozygous MTHFR 677C/T polymorphisms were higher in DVT patients compared with the control group (OR=6.65, 95% CI=3.09-14.30 and OR=4.08, 95% CI=1.35-12.38, respectively).
|
26261166 |
2015 |
|
Deep Vein Thrombosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
PAI-1 4G/5G and MTHFR C677T polymorphisms increased the accuracy of two prediction scores for the risk of acute lower extremity deep vein thrombosis.
|
24715181 |
2014 |
|
Deep Vein Thrombosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
The homozygous 20209C>T mutation and the presence of the mutation 677C>T in heterozygosity explained the patient's deep vein thrombosis because the combination of mutations would increase the risk of thrombosis.
|
24627725 |
2014 |
|
Deep Vein Thrombosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
However, the frequency of the MTHFR C677T polymorphism was significantly higher in patients with SVT compared with DVT (CT 12 versus 10, and TT 7 versus 1, respectively, P < 0.001).
|
20881312 |
2011 |
|
Deep Vein Thrombosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
In addition, only MTHFR C677T polymorphism constituted a molecular biomarker of DVT in Chilean population.
|
20707729 |
2010 |
|
Deep Vein Thrombosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
The aim of present study was to investigate the prevalence of factor V Leiden (FVL) c.1691G>A, prothrombin g.20210G>A and methylenetetrahydrofolate reductase (MTHFR) c.677C>T in deep vein thrombosis (DVT) patients and their possible association with DVT in western Iran.
|
20479641 |
2010 |
|
Deep Vein Thrombosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
Patients with homozygous or combined heterozygous status of MTHFR C677T and A1298C mutation had a higher frequency of DVT after elective THA (odds ratio, 2.86; 95% confidence interval, 1.32-6.35) than those with wild-type.
|
18800213 |
2009 |
|
Deep Vein Thrombosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
We conclude that MTHFR C677T and MTHFR A1289C genotypes and haplotypes are connected with tHcy plasma levels in Macedonian patients with OAD and DVT.
|
18800176 |
2008 |
|
Deep Vein Thrombosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
We studied prothrombotic determinants, namely protein C, protein S, and AT along with factor V Leiden (1691G-->A), prothrombin gene mutation (20210G-->A), CBS 844ins68 mutation, and MTHFR mutation (677C-->T) in consecutive ethnic Omani patients with first episode of a thrombophilic event, namely, deep vein thrombosis (DVT), and/or pulmonary embolism (PE) or thrombosis at an unusual site.
|
16432849 |
2006 |
|
Deep Vein Thrombosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
This indicates that FV-Leiden and PRT G20210A, more than MTHFR C677T, are important risk factors for DVT, and that the presence of more than one prothrombotic SNPs was associated with a significant risk of DVT.
|
16082606 |
2005 |
|
Deep Vein Thrombosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
To determine the incidence of deep venous thrombosis (DVT) recurrence in young people, and its association with some genetic polymorphisms (FV G1691A, FII G20210A, MTHFR C677T, PAI-1 4G/5G).
|
16061406 |
2005 |
|
Deep Vein Thrombosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
The aim of this study was to assess whether homozygosity for the 5, 10-methylenetetrahydrofolate reductase (MTHFR) C677T mutation and plasma homocysteine concentration are related to deep vein thrombosis in Behçet's disease (BD) patients.
|
14504916 |
2003 |
|
Deep Vein Thrombosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
The prevalences of the C677T and A1298C genotypes did not differ significantly in 772 individuals with documented coronary artery disease (CAD), 137 individuals with deep-vein thrombosis (DVT), and 329 individuals without documented vascular disease.
|
11274015 |
2001 |
|
Deep Vein Thrombosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
MTHFR gene C677T mutation does not increase risk of DVT in BD either alone or combined with FV Leiden mutation.
|
11128675 |
2000 |
|
Deep Vein Thrombosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
We investigated the prevalence of MTHFR C677T and prothrombin G20210A genotypes by polymerase chain reaction (PCR) followed by restriction enzyme digestion in 420 Chinese subjects: 53 with deep venous thrombosis (DVT); 145 with cerebrovascular disease [115 cerebral infarction, 30 cerebral haemorrhage (CH)]; 100 with coronary artery disease (CAD); and 122 control subjects.
|
10929044 |
2000 |
|
Deep Vein Thrombosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
Common C677T polymorphism in the methylenetetrahydrofolate reductase gene increases the risk for deep vein thrombosis in patients with predisposition of thrombophilia.
|
10706928 |
2000 |
|
Deep Vein Thrombosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
These data indicated that the C677T MTHF gene mutation was not associated with DVT in the Thai population.
|
11014892 |
2000 |
|
Deep Vein Thrombosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
We calculated the prevalences of prothrombin G20210A, factor V G1691A (also associated with high risk for DVT) and homozygous methylenetetrahydrofolate reductase (MTHFR) C677T (associated with increased susceptibility to develop hyperhomocysteinemia) in 118 patients with a first episode of DVT and in 416 healthy controls.
|
10065893 |
1999 |
|
Deep Vein Thrombosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
In the same individuals, we also evaluated the frequency of the coexistence of C677T MTHFR with mutant factor V:Q506, a common risk factor for deep-vein thrombosis.
|
9327760 |
1997 |