rs1217691063, MTHFR

N. diseases: 614
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Dyslipidemias
CUI: C0242339
Disease: Dyslipidemias
0.040 GeneticVariation BEFREE Further studies are needed to confirm the role of tHcy and the MTHFR C677T mutation in the development of dyslipidemia in a larger sample. 26442927 2017
Dyslipidemias
CUI: C0242339
Disease: Dyslipidemias
0.040 GeneticVariation BEFREE In conclusion, in these type 2 diabetic outpatients circulating levels of tHcy, folate, and the MTHFR C677T mutation are not associated with DPN, which was predicted by creatinine levels, CHD, and dyslipidemia. 26233336 2016
Dyslipidemias
CUI: C0242339
Disease: Dyslipidemias
0.040 GeneticVariation BEFREE Supplementation with Watermelon Extract Reduces Total Cholesterol and LDL Cholesterol in Adults with Dyslipidemia under the Influence of the MTHFR C677T Polymorphism. 26934084 2016
Dyslipidemias
CUI: C0242339
Disease: Dyslipidemias
0.040 GeneticVariation BEFREE The aim of the present study was to evaluate the effect of simvastatin treatment on circulating Hcy levels in obese women without hypertension, diabetes or dyslipidaemia; and to determine whether the 677C>T polymorphism located in methylenetetrahydrofolate reductase (NAD(P)H) (MTHFR) gene modulates the effects of this treatment on Hcy and nitrite (as a biomarker of nitric oxide (NO) bioavailability). 25115547 2014