rs121909218, PTEN

N. diseases: 25
Disease: Tumor Cell Invasion ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Tumor Cell Invasion
CUI: C1269955
Disease: Tumor Cell Invasion
0.020 GeneticVariation BEFREE Results indicate that the G129E mutant blocks invasion as efficiently as wild-type PTEN transfection. 15273733 2004
Tumor Cell Invasion
CUI: C1269955
Disease: Tumor Cell Invasion
0.020 GeneticVariation BEFREE Ectopic expressions of adenoviral (Ad)-wt-PTEN and -lipid phosphatase-deficient (G129E)-PTEN, but not both protein and -lipid phosphatase-deficient (C124S)-PTEN, reduced MMP-9 secretion and invasion by HA. 12414663 2002