|
Li-Fraumeni Syndrome
|
|
0.820 |
CausalMutation
|
CLINVAR |
Germline TP53 mutational spectrum in French Canadians with breast cancer.
|
25925845 |
2015 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
GeneticVariation
|
UNIPROT |
American Society of Clinical Oncology Expert Statement: collection and use of a cancer family history for oncology providers.
|
24493721 |
2014 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
CausalMutation
|
CLINVAR |
Unequal prognostic potentials of p53 gain-of-function mutations in human cancers associate with drug-metabolizing activity.
|
24603336 |
2014 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
CausalMutation
|
CLINVAR |
Clinical response to a lapatinib-based therapy for a Li-Fraumeni syndrome patient with a novel HER2V659E mutation.
|
23950206 |
2013 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
CausalMutation
|
CLINVAR |
A young woman with bilateral breast cancer: identifying a genetic cause and implications for management.
|
23667202 |
2013 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
GeneticVariation
|
CLINVAR |
FOXM1 is a molecular determinant of the mitogenic and invasive phenotype of anaplastic thyroid carcinoma.
|
22919068 |
2012 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
CausalMutation
|
CLINVAR |
Mutant p53: one name, many proteins.
|
22713868 |
2012 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
GeneticVariation
|
CLINVAR |
Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes.
|
21343334 |
2011 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
GeneticVariation
|
CLINVAR |
Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a prospective observational study.
|
21601526 |
2011 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
CausalMutation
|
CLINVAR |
TP53 germline mutation testing in 180 families suspected of Li-Fraumeni syndrome: mutation detection rate and relative frequency of cancers in different familial phenotypes.
|
20522432 |
2010 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
CausalMutation
|
CLINVAR |
Here, we report a family with LFS harboring a germline TP53 mutation (R248W) located in the functional domain of the protein that binds to the minor groove of the DNA.
|
19378321 |
2009 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
GeneticVariation
|
BEFREE |
Here, we report a family with LFS harboring a germline TP53 mutation (R248W) located in the functional domain of the protein that binds to the minor groove of the DNA.
|
19378321 |
2009 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
GeneticVariation
|
BEFREE |
It remains unclear at this time whether a similar association of NB and R248W in patients with LFS exists.
|
17427234 |
2008 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
CausalMutation
|
CLINVAR |
It remains unclear at this time whether a similar association of NB and R248W in patients with LFS exists.
|
17427234 |
2008 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
CausalMutation
|
CLINVAR |
Transcriptional functionality of germ line p53 mutants influences cancer phenotype.
|
17606709 |
2007 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
GeneticVariation
|
CLINVAR |
Transcriptional functionality of germ line p53 mutants influences cancer phenotype.
|
17606709 |
2007 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
GeneticVariation
|
UNIPROT |
American Cancer Society guidelines for breast screening with MRI as an adjunct to mammography.
|
17392385 |
2007 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
CausalMutation
|
CLINVAR |
p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM.
|
17417627 |
2007 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
GeneticVariation
|
CLINVAR |
Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis.
|
12826609 |
2003 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
GeneticVariation
|
CLINVAR |
Complex functions of mutant p53 alleles from human prostate cancer.
|
11920959 |
2002 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
GeneticVariation
|
UNIPROT |
Hereditary TP53 codon 292 and somatic P16INK4A codon 94 mutations in a Li-Fraumeni syndrome family.
|
10484981 |
1999 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
CausalMutation
|
CLINVAR |
Simultaneous adrenocortical carcinoma and ganglioneuroblastoma in a child with Turner syndrome and germline p53 mutation.
|
9598730 |
1998 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
CausalMutation
|
CLINVAR |
Astrocytomas and choroid plexus tumors in two families with identical p53 germline mutations.
|
9825943 |
1998 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
GeneticVariation
|
UNIPROT |
A germline missense mutation R337C in exon 10 of the human p53 gene.
|
9452042 |
1998 |
|
Li-Fraumeni Syndrome
|
|
0.820 |
CausalMutation
|
CLINVAR |
Germ-line mutations of TP53 in Li-Fraumeni families: an extended study of 39 families.
|
9242456 |
1997 |