rs121913237, NRAS

N. diseases: 50
Disease: Myeloproliferative disease ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Myeloproliferative disease
CUI: C0027022
Disease: Myeloproliferative disease
0.030 GeneticVariation BEFREE Further, one of the patients (c.35G>A; p.(Gly12Asp)) had a myeloproliferative disorder, and one subject (c.34G>C; p.(Gly12Arg)) exhibited an uncharacterized brain tumour. 28594414 2017
Myeloproliferative disease
CUI: C0027022
Disease: Myeloproliferative disease
0.030 GeneticVariation BEFREE Expressing oncogenic Nras(G12D) in the hematopoietic compartment of mice induces an aggressive myeloproliferative neoplasm that is exacerbated in homozygous mutant animals. 23733505 2013
Myeloproliferative disease
CUI: C0027022
Disease: Myeloproliferative disease
0.030 GeneticVariation BEFREE The disease phenotype in Mx1-Cre, LSL-Nras(G12D) mice is attenuated compared with Mx1-Cre, LSL-Kras(G12D) mice, which die of aggressive myeloproliferative disorder by 4 months of age. 21163920 2011