Disease | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
Liver carcinoma
|
0.800 | CausalMutation | CLINVAR | ||||||||
NEVUS, EPIDERMAL (disorder)
|
0.710 | CausalMutation | CLINVAR | ||||||||
Colorectal Carcinoma
|
0.700 | CausalMutation | CLINVAR | ||||||||
Colorectal Neoplasms
|
0.700 | CausalMutation | CLINVAR | High frequency of mutations of the PIK3CA gene in human cancers. | 15016963 | 2004 | |||||
Colorectal Neoplasms
|
0.700 | CausalMutation | CLINVAR | High frequency of mutations of the PIK3CA gene in human cancers. | 15016963 | 2004 | |||||
Colorectal Neoplasms
|
0.700 | CausalMutation | CLINVAR | High frequency of mutations of the PIK3CA gene in human cancers. | 15016963 | 2004 | |||||
Colorectal Neoplasms
|
0.700 | CausalMutation | CLINVAR | The PIK3CA gene is mutated with high frequency in human breast cancers. | 15254419 | 2004 | |||||
Colorectal Neoplasms
|
0.700 | CausalMutation | CLINVAR | The PIK3CA gene is mutated with high frequency in human breast cancers. | 15254419 | 2004 | |||||
Mammary Neoplasms
|
0.700 | CausalMutation | CLINVAR | The PIK3CA gene is mutated with high frequency in human breast cancers. | 15254419 | 2004 | |||||
Colorectal Neoplasms
|
0.700 | CausalMutation | CLINVAR | The PIK3CA gene is mutated with high frequency in human breast cancers. | 15254419 | 2004 | |||||
Mammary Neoplasms
|
0.700 | CausalMutation | CLINVAR | The PIK3CA gene is mutated with high frequency in human breast cancers. | 15254419 | 2004 | |||||
Mammary Neoplasms
|
0.700 | CausalMutation | CLINVAR | The PIK3CA gene is mutated with high frequency in human breast cancers. | 15254419 | 2004 | |||||
Liver carcinoma
|
0.800 | GeneticVariation | UNIPROT | PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas. | 15608678 | 2005 | |||||
Colorectal Neoplasms
|
0.700 | CausalMutation | CLINVAR | Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. | 15647370 | 2005 | |||||
ovarian neoplasm
|
0.700 | CausalMutation | CLINVAR | Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. | 15647370 | 2005 | |||||
Mammary Neoplasms
|
0.700 | CausalMutation | CLINVAR | Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. | 15647370 | 2005 | |||||
Mammary Neoplasms
|
0.700 | CausalMutation | CLINVAR | Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. | 15647370 | 2005 | |||||
Colorectal Neoplasms
|
0.700 | CausalMutation | CLINVAR | Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. | 15647370 | 2005 | |||||
Colorectal Neoplasms
|
0.700 | CausalMutation | CLINVAR | Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. | 15647370 | 2005 | |||||
Mammary Neoplasms
|
0.700 | CausalMutation | CLINVAR | Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. | 15647370 | 2005 | |||||
Mammary Neoplasms
|
0.700 | CausalMutation | CLINVAR | PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma. | 15805248 | 2005 | |||||
Mammary Neoplasms
|
0.700 | CausalMutation | CLINVAR | PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma. | 15805248 | 2005 | |||||
Mammary Neoplasms
|
0.700 | CausalMutation | CLINVAR | PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma. | 15805248 | 2005 | |||||
NEVUS, EPIDERMAL (disorder)
|
0.710 | GeneticVariation | BEFREE | Nine of 33 (27%) EN harbored PIK3CA mutations; all cases showed the E545G substitution, which is uncommon in cancers. | 17673550 | 2007 | |||||
Seborrheic keratosis
|
0.700 | GeneticVariation | UNIPROT | Oncogenic PIK3CA mutations occur in epidermal nevi and seborrheic keratoses with a characteristic mutation pattern. | 17673550 | 2007 |