rs121913279, PIK3CA

N. diseases: 101
Disease: Colorectal Carcinoma ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Colorectal Carcinoma
CUI: C0009402
Disease: Colorectal Carcinoma
0.820 GeneticVariation BEFREE We developed a sensitive, simple and rapid approach to detect the low-abundance PIK3CA (H1047R) mutation in real CRC specimens, providing an effective tool for guiding cancer targeted therapy. 27405731 2016
Colorectal Carcinoma
CUI: C0009402
Disease: Colorectal Carcinoma
0.820 GeneticVariation BEFREE Collectively, our data suggest that PF-04691502 exhibits potent anticancer activity in colorectal cancer by targeting both PIK3CA (H1047R) mutant CSCs and their derivatives. 23826249 2013
Colorectal Carcinoma
CUI: C0009402
Disease: Colorectal Carcinoma
0.820 GeneticVariation UNIPROT The prevalence of PIK3CA mutations in gastric and colon cancer. 15994075 2005
Colorectal Carcinoma
CUI: C0009402
Disease: Colorectal Carcinoma
0.820 GeneticVariation UNIPROT Functional analysis of PIK3CA gene mutations in human colorectal cancer. 15930273 2005
Colorectal Carcinoma
CUI: C0009402
Disease: Colorectal Carcinoma
0.820 CausalMutation CLINVAR