rs121913499, IDH1

N. diseases: 51
Disease: Adult Fibrosarcoma ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Adult Fibrosarcoma
CUI: C0278595
Disease: Adult Fibrosarcoma
0.010 GeneticVariation BEFREE Here, using a genetically engineered inducible system, we report that selective suppression of endogenous mutant IDH1 expression in HT1080, a fibrosarcoma cell line with a native IDH1(R132C) heterozygous mutation, significantly inhibits cell proliferation and decreases clonogenic potential. 22885298 2012