rs121913529, KRAS

N. diseases: 144
Disease: Secondary malignant neoplasm of colon and/or rectum ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Secondary malignant neoplasm of colon and/or rectum
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
0.030 GeneticVariation BEFREE To limit these variables, we previously studied a patient with metastatic colorectal cancer treated with polyclonal TILs targeting the <i>KRAS</i>(G12D) hotspot mutation, who experienced a partial response for 9 months. 31484655 2019
Secondary malignant neoplasm of colon and/or rectum
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
0.030 GeneticVariation BEFREE G12V and G12A KRAS mutations are associated with poor outcome in patients with metastatic colorectal cancer treated with bevacizumab. 26662311 2016
Secondary malignant neoplasm of colon and/or rectum
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
0.030 GeneticVariation BEFREE We identified a polyclonal CD8+ T-cell response against mutant KRAS G12D in tumor-infiltrating lymphocytes obtained from a patient with metastatic colorectal cancer. 27959684 2016