rs121913530, KRAS

N. diseases: 63
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
polyps
CUI: C0032584
Disease: polyps
0.020 GeneticVariation BEFREE There was a strong association between germinal MUTYH mutation and KRAS Gly12Cys somatic mutation in polyps. 24470512 2014
polyps
CUI: C0032584
Disease: polyps
0.020 GeneticVariation BEFREE The analysis of MUTYH-associated polyposis cases of the EPIPOLIP cohort confirms the importance of including serrated polyps in the diagnostic work-up of patients with oligopolyposis, suggests a role for screening polyps for the somatic c.34G>T KRAS mutation, and allows the implementation of a genetic testing strategy based on population data. 24486588 2014