rs121918338, CARD9

N. diseases: 7
Disease: Central Nervous System Infection ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Central Nervous System Infection
CUI: C0007684
Disease: Central Nervous System Infection
0.010 GeneticVariation BEFREE Patients with the mutations R18W, R35Q, R70W, G72S or Y91H in the CARD domain, and the nonsense mutation Q295X in the coiled-coil domain, seemed to be more prone to Candida infections (90% vs. 20%, P < 0·005) and central nervous system infections (60% vs. 12%, P < 0·005). 30117151 2019