rs12255372, TCF7L2

N. diseases: 28
Disease: Metabolic Syndrome X ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.030 GeneticVariation BEFREE The presence of the rs12255372 and rs7903146 TCF7L2 gene variants plays an important role in the development of T2DM among individuals with MS. 29971604 2018
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.030 GeneticVariation BEFREE The two markers located within the TCF7L2 gene showed strong associations with T2D (rs7903146, T allele, odd ratio (OR) = 1.76, p = 0.001 and rs12255372, T allele, OR = 1.78, p = 0.002), but did not show significant association with MS. 20503258 2010
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.030 GeneticVariation BEFREE We investigated the effect of single nucleotide polymorphisms (SNP), rs7903146 and rs12255372, within the TCF7L2 locus on postprandial lipemia and other MetS-related traits and their modulation by dietary fat. 19141698 2009