rs12526453, PHACTR1

N. diseases: 5
Disease: Coronary Artery Disease ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.730 GeneticVariation BEFREE In the present study, we have shown that the rs12526453 single-nucleotide polymorphism of the PHACTR1 gene is significantly associated with a 50% reduction in the odds of CAD events in FH subjects. 29784573 2019
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.730 GeneticVariation BEFREE Our results showed that the polymorphisms rs1252</span>6453 and rs11066301 are significantly associated with the CAD risk in multiple populations. 25123136 2014
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.730 GeneticVariation BEFREE Besides the CAD/MI SNP at 9p21 (rs4977574, P = 3.1 × 10(-10)), two additional loci at ADAMTS7 (rs3825807, P = 6.5 × 10(-6)) and at PHACTR1 (rs12526453, P = 1.0 × 10(-3)) show a nominally significant association with coronary artery calcification with MI/CAD risk alleles increasing the degree of arterial calcification. 23561647 2013
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.730 GeneticVariation GWASDB Large-scale association analysis identifies new risk loci for coronary artery disease. 23202125 2013