rs12540874, GRB10

N. diseases: 3
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Systemic Scleroderma
CUI: C0036421
Disease: Systemic Scleroderma
0.800 GeneticVariation GWASCAT Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy. 21779181 2011
Systemic Scleroderma
CUI: C0036421
Disease: Systemic Scleroderma
0.800 GeneticVariation GWASDB Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy. 21779181 2011
Precursor Cell Lymphoblastic Leukemia Lymphoma
CUI: C1961102
Disease: Precursor Cell Lymphoblastic Leukemia Lymphoma
0.700 GeneticVariation GWASDB Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations. 23512250 2013
CREST Syndrome
CUI: C0206138
Disease: CREST Syndrome
0.010 GeneticVariation BEFREE Also, rs12540874 in GRB10 gene (P = 1.27 × 10(-6), OR = 1.15) and rs11047102 in SOX5 gene (P = 1.39×10(-7), OR = 1.36) showed a suggestive association with lcSSc and ACA subgroups respectively. 21779181 2011