FASTING PLASMA GLUCOSE LEVEL QUANTITATIVE TRAIT LOCUS 5
|
|
0.700 |
GeneticVariation
|
CLINVAR |
|
|
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Common genetic variation near MC4R is associated with waist circumference and insulin resistance.
|
18454146 |
2008 |
High density lipoprotein measurement
|
|
0.700 |
GeneticVariation
|
GWASDB |
Common genetic variation near MC4R is associated with waist circumference and insulin resistance.
|
18454146 |
2008 |
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.770 |
GeneticVariation
|
BEFREE |
The common P446L polymorphism in GCKR inversely modulates fasting glucose and triglyceride levels and reduces type 2 diabetes risk in the DESIR prospective general French population.
|
18556336 |
2008 |
Dyslipidemias
|
|
0.030 |
GeneticVariation
|
BEFREE |
We evaluated, in a general French population, the contribution of the GCKR rs1260326-P446L polymorphism to quantitative metabolic parameters and to dyslipidemia and hyperglycemia risk.
|
18556336 |
2008 |
Hyperglycemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
Moreover, an additive effect of GCKR rs1260326(T) and GCK (-30G) alleles conferred lower fasting glycemia (P = 1 x 10(-13)), insulinemia (P = 5 x 10(-6)), and hyperglycemia risk (P = 1 x 10(-6)).
|
18556336 |
2008 |
Metabolic Syndrome X
|
|
0.040 |
GeneticVariation
|
BEFREE |
A polymorphism in the GCKR gene predicted dyslipidaemia (rs1260326, OR 1.15, 95% CI 1.09-1.22, p < 0.00001) but not the metabolic syndrome.
|
18853134 |
2008 |
Dyslipidemias
|
|
0.030 |
GeneticVariation
|
BEFREE |
A polymorphism in the GCKR gene predicted dyslipidaemia (rs1260326, OR 1.15, 95% CI 1.09-1.22, p < 0.00001) but not the metabolic syndrome.
|
18853134 |
2008 |
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Common variants at 30 loci contribute to polygenic dyslipidemia.
|
19060906 |
2009 |
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Common variants at 30 loci contribute to polygenic dyslipidemia.
|
19060906 |
2009 |
elevated blood glucose level
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
|
19060910 |
2009 |
Glucose measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
|
19060910 |
2009 |
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
|
19060910 |
2009 |
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
|
19060911 |
2009 |
Uric acid measurement (procedure)
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|
0.800 |
GeneticVariation
|
GWASDB |
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.
|
19503597 |
2009 |
Lipids measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.
|
19936222 |
2009 |
Glucose tolerance test
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.
|
20081857 |
2010 |
Glucose tolerance test
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.
|
20081857 |
2010 |
Triglycerides measurement
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|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of hematological and biochemical traits in a Japanese population.
|
20139978 |
2010 |
Serum albumin measurement
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|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of hematological and biochemical traits in a Japanese population.
|
20139978 |
2010 |
Chronic Kidney Diseases
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|
0.710 |
GeneticVariation
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GWASDB |
New loci associated with kidney function and chronic kidney disease.
|
20383146 |
2010 |
Creatinine measurement, serum (procedure)
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|
0.700 |
GeneticVariation
|
GWASCAT |
New loci associated with kidney function and chronic kidney disease.
|
20383146 |
2010 |
Kidney Failure, Chronic
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|
0.700 |
GeneticVariation
|
GWASCAT |
New loci associated with kidney function and chronic kidney disease.
|
20383146 |
2010 |
Hypertriglyceridemia
|
|
0.820 |
GeneticVariation
|
GWASDB |
Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia.
|
20657596 |
2010 |
Hypertriglyceridemia
|
|
0.820 |
GeneticVariation
|
GWASCAT |
Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia.
|
20657596 |
2010 |