|
FASTING PLASMA GLUCOSE LEVEL QUANTITATIVE TRAIT LOCUS 5
|
|
0.700 |
GeneticVariation
|
CLINVAR |
|
|
|
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A genome wide association study identifies common variants associated with lipid levels in the Chinese population.
|
24386095 |
2013 |
|
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
A genome wide association study identifies common variants associated with lipid levels in the Chinese population.
|
24386095 |
2013 |
|
Factor VII measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.
|
30642921 |
2019 |
|
Hepatitis B
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population.
|
21750111 |
2011 |
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
|
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
|
Low density lipoprotein cholesterol measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
|
Dyslipidemias
|
|
0.030 |
GeneticVariation
|
BEFREE |
A polymorphism in the GCKR gene predicted dyslipidaemia (rs1260326, OR 1.15, 95% CI 1.09-1.22, p < 0.00001) but not the metabolic syndrome.
|
18853134 |
2008 |
|
Metabolic Syndrome X
|
|
0.040 |
GeneticVariation
|
BEFREE |
A polymorphism in the GCKR gene predicted dyslipidaemia (rs1260326, OR 1.15, 95% CI 1.09-1.22, p < 0.00001) but not the metabolic syndrome.
|
18853134 |
2008 |
|
Non-alcoholic Fatty Liver Disease
|
|
0.760 |
GeneticVariation
|
BEFREE |
Additionally, our results suggest Asian-specific, liver biopsy-specific, adult-specific and pediatric-specific associations between the rs1260326 and NAFLD.
|
30646922 |
2019 |
|
Non-alcoholic Fatty Liver Disease
|
|
0.760 |
GeneticVariation
|
BEFREE |
Among individual variants, rs1260326 in GCKR and rs641738 in MBOAT7 (recessive), rs58542926 in TM6SF2 and rs738409 in PNPLA3 (dominant) emerged as associated to NAFLD, with PNPLA3 rs738409 being the strongest predictor (OR 3.12, 95% CI, 1.8-5.5, P < 0.001).
|
29487372 |
2018 |
|
Colorectal Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Among the 19 CRP-associated SNPs, rs1260326 and rs6734238 were significantly associated with CRC risk (P = 7.5 × 10-4, and P = 0.003, respectively).
|
30476131 |
2019 |
|
Non-alcoholic Fatty Liver Disease
|
|
0.760 |
GeneticVariation
|
BEFREE |
Among the eleven genotyped SNPs, the genetic variants in TM6SF2 rs58542926 (OR = 4.13, p = 0.002), GCKR rs1260326 (OR = 1.53, p = 0.003), PNPLA3 rs738409 (OR = 1.58, p = 0.004) and ELOVL2 rs2236212 (OR = 1.34, p = 0.047) were significantly associated with a higher risk of NAFLD.
|
31255630 |
2019 |
|
Cholangitis, Sclerosing
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
|
26974007 |
2016 |
|
Ulcerative Colitis
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
|
26974007 |
2016 |
|
Psoriasis
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
|
26974007 |
2016 |
|
Ankylosing spondylitis
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
|
26974007 |
2016 |
|
Crohn Disease
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
|
26974007 |
2016 |
|
Inflammatory Bowel Diseases
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
|
26192919 |
2015 |
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
|
28334899 |
2017 |
|
Serum albumin measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese.
|
22558069 |
2012 |
|
Serum albumin measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese.
|
22558069 |
2012 |
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Biological, clinical and population relevance of 95 loci for blood lipids.
|
20686565 |
2010 |
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Biological, clinical and population relevance of 95 loci for blood lipids.
|
20686565 |
2010 |