Prostate carcinoma
|
|
0.740 |
GeneticVariation
|
GWASCAT |
Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.
|
20676098 |
2010 |
Malignant neoplasm of prostate
|
|
0.740 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.
|
20676098 |
2010 |
Malignant neoplasm of prostate
|
|
0.740 |
GeneticVariation
|
BEFREE |
The rs12653946 SNP at 5p15 was found to be significantly associated with prostate cancer risk (odds ratio = 1.20, 95% confidence interval: 1.07, 1.34; P = 0.002).
|
22085625 |
2011 |
Prostate carcinoma
|
|
0.740 |
GeneticVariation
|
BEFREE |
The rs12653946 SNP at 5p15 was found to be significantly associated with prostate cancer risk (odds ratio = 1.20, 95% confidence interval: 1.07, 1.34; P = 0.002).
|
22085625 |
2011 |
Malignant neoplasm of prostate
|
|
0.740 |
GeneticVariation
|
BEFREE |
We found that three of the five genetic variants were associated with prostate cancer risk (P = 4.33 × 10(-8) for rs12653946 at 5p15, 4.43 × 10(-5) for rs339331 at 6q22 and 8.42 × 10(-4) for rs9600079 at 13q22, respectively).
|
22114074 |
2012 |
Prostate carcinoma
|
|
0.740 |
GeneticVariation
|
BEFREE |
These findings indicate that the PC-susceptibility locus represented by rs12653946 at 5p15 is likely to regulate IRX4 expression in prostate which could suppress PC growth by interacting with the VDR pathway, conferring to PC susceptibility.
|
22323358 |
2012 |
Malignant neoplasm of prostate
|
|
0.740 |
GeneticVariation
|
BEFREE |
These findings indicate that the PC-susceptibility locus represented by rs12653946 at 5p15 is likely to regulate IRX4 expression in prostate which could suppress PC growth by interacting with the VDR pathway, conferring to PC susceptibility.
|
22323358 |
2012 |
Prostate carcinoma
|
|
0.740 |
GeneticVariation
|
BEFREE |
We successfully replicated the association of rs13385191 (located in the C2orf43 gene, P = 8.60×10(-5)), rs12653946 (P = 1.33×10(-6)), rs1983891 (FOXP4, P = 6.22×10(-5)), and rs339331 (GPRC6A/RFX6, P = 1.42×10(-5)) with prostate cancer.
|
22662242 |
2012 |
Prostate carcinoma
|
|
0.740 |
GeneticVariation
|
BEFREE |
We found that three of the five genetic variants were associated with prostate cancer risk (P = 4.33 × 10(-8) for rs12653946 at 5p15, 4.43 × 10(-5) for rs339331 at 6q22 and 8.42 × 10(-4) for rs9600079 at 13q22, respectively).
|
22114074 |
2012 |
Prostate carcinoma
|
|
0.740 |
GeneticVariation
|
GWASCAT |
Evaluating genetic risk for prostate cancer among Japanese and Latinos.
|
22923026 |
2012 |
Malignant neoplasm of prostate
|
|
0.740 |
GeneticVariation
|
GWASDB |
Evaluating genetic risk for prostate cancer among Japanese and Latinos.
|
22923026 |
2012 |
Malignant neoplasm of prostate
|
|
0.740 |
GeneticVariation
|
BEFREE |
We successfully replicated the association of rs13385191 (located in the C2orf43 gene, P = 8.60×10(-5)), rs12653946 (P = 1.33×10(-6)), rs1983891 (FOXP4, P = 6.22×10(-5)), and rs339331 (GPRC6A/RFX6, P = 1.42×10(-5)) with prostate cancer.
|
22662242 |
2012 |
Primary malignant neoplasm
|
|
0.010 |
GeneticVariation
|
BEFREE |
We genotyped five single-nucleotide polymorphism (SNP): rs13385191 (chromosome 2p24), rs12653946 (5p15), rs1983891 (6p21), rs339331 (6p22), and rs9600079 (13q22), in 7,956 prostate cancer cases and 8,148 controls from a series of nested case-control studies within the National cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3).
|
22056501 |
2012 |
Malignant Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
We genotyped five single-nucleotide polymorphism (SNP): rs13385191 (chromosome 2p24), rs12653946 (5p15), rs1983891 (6p21), rs339331 (6p22), and rs9600079 (13q22), in 7,956 prostate cancer cases and 8,148 controls from a series of nested case-control studies within the National cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3).
|
22056501 |
2012 |
Malignant neoplasm of prostate
|
|
0.740 |
GeneticVariation
|
GWASDB |
Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population.
|
23555315 |
2013 |
Benign Prostatic Hyperplasia
|
|
0.010 |
GeneticVariation
|
BEFREE |
In addition, rs12621278 (OR = 0.73, P = 0.05) and rs12653946, 13 kb upstream of IRX4 at 5p15 (OR = 1.40, 0.03), were significantly associated with aggressive BPH.
|
23620269 |
2013 |
Prostate carcinoma
|
|
0.740 |
GeneticVariation
|
GWASCAT |
Large-scale association analysis in Asians identifies new susceptibility loci for prostate cancer.
|
26443449 |
2015 |
Prostate carcinoma
|
|
0.740 |
GeneticVariation
|
GWASCAT |
12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population.
|
31562322 |
2019 |