|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of blood lipids in Indians confirms universality of established variants.
|
30911093 |
2019 |
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
A genome-wide association and gene-environment interaction study for serum triglycerides levels in a healthy Chinese male population.
|
22171074 |
2012 |
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Here we apply an EMR-based phenotyping approach, within the context of routine care, to replicate several known associations between HDL-C and previously characterized genetic variants: CETP (rs3764261, p = 1.22e-25), LIPC (rs11855284, p = 3.92e-14), LPL (rs12678919, p = 1.99e-7), and the APOA1/C3/A4/A5 locus (rs964184, p = 1.06e-5), all adjusted for age, gender, body mass index (BMI), and smoking status.
|
21589926 |
2011 |
|
Calcification of coronary artery
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
|
22916037 |
2012 |
|
Serum HDL cholesterol measurement
|
|
0.700 |
GeneticVariation
|
GWASDB |
Knowledge-driven multi-locus analysis reveals gene-gene interactions influencing HDL cholesterol level in two independent EMR-linked biobanks.
|
21589926 |
2011 |
|
Serum albumin measurement
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies multiple loci influencing human serum metabolite levels.
|
22286219 |
2012 |
|
Coronary heart disease
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
|
21347282 |
2011 |
|
Serum HDL cholesterol measurement
|
|
0.700 |
GeneticVariation
|
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
Pseudocholinesterase Measurement
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.
|
21943158 |
2011 |
|
Age related macular degeneration
|
|
0.040 |
GeneticVariation
|
BEFREE |
Individuals carrying the lipoprotein lipase (LPL) rs12678919 polymorphism (A → G) had no significant change in the risk of developing AMD (OR = 1.01, CI: 0.92-1.10, P = 0.17).
|
26503844 |
2015 |
|
Age related macular degeneration
|
|
0.040 |
GeneticVariation
|
BEFREE |
After multivariate adjustment for age, sex, educational level, smoking, BMI, lipid-lowering medication use, cardiovascular disease and diabetes, and for all relevant genetic polymorphisms (ApoE2, ApoE4, CFH Y402H, ARMS2 A69S, LIPC rs10468017, LIPC rs493258, LPL rs12678919, ABCA1 rs1883025 and CETP rs3764261), higher HDL was significantly associated with an increased risk of early (OR = 2.45, 95%CI: 1.54-3.90; P = 0.0002) and any AMD (OR = 2.29, 95%CI: 1.46-3.59; P = 0.0003).
|
24608419 |
2014 |
|
Age related macular degeneration
|
|
0.040 |
GeneticVariation
|
BEFREE |
SIRT1 rs12778366, FGFR2 rs2981582, STAT3 rs744166, LIPC rs10468017, rs493258 and LPL rs12678919 genotypes and haplotype evaluation in patients with age-related macular degeneration.
|
30399423 |
2019 |
|
Age related macular degeneration
|
|
0.040 |
GeneticVariation
|
BEFREE |
Rs10468017 in LIPC, rs12678919 near LPL and rs1883025 in ABCA1 were not found to be associated with advanced AMD (all p > 0.05).
|
24498989 |
2015 |
|
Polypoidal choroidal vasculopathy
|
|
0.020 |
GeneticVariation
|
BEFREE |
LIPC rs493258 and LPL rs12678919 did not show significant associations with the development of PCV (P > 0.05).
|
23950155 |
2013 |
|
Polypoidal choroidal vasculopathy
|
|
0.020 |
GeneticVariation
|
BEFREE |
We found no association between PCV and LPL rs12678919, LIPC rs10468017 or CETP rs173539.
|
26624898 |
2015 |
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of serum lipids confirms previously reported associations as well as new associations of common SNPs within PCSK7 gene with triglyceride.
|
26763881 |
2016 |
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
|
28334899 |
2017 |
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.
|
26582766 |
2016 |
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
|
30926973 |
2019 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |