|
Hepatitis B
|
|
0.100 |
GeneticVariation
|
BEFREE |
These results suggest that rs12979860 does not have such a strong effect in hepatitis B compared to hepatitis C.
|
22239156 |
2012 |
|
Hepatitis B
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our results suggest that the IL28B rs12979860 C/T polymorphism might affect susceptibility to the chronic HBV infection and progression of HCC.
|
22310928 |
2012 |
|
Hepatitis B
|
|
0.100 |
GeneticVariation
|
BEFREE |
To evaluate the role of host IL28B (interleukin 28B; interferon lambda 3) single nucleotide polymorphisms (SNPs) in predicting hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) susceptibility, three SNPs in the IL28B gene (rs12979860C/T, rs8099917G/T and rs12980275G/A) were examined in 330 subjects (including 154 HBV-related HCC patients, 86 non-HCC patients with chronic hepatitis B (CHB), 43 HBV self-limited infections and 47 healthy controls).
|
22310928 |
2012 |
|
Hepatitis B
|
|
0.100 |
GeneticVariation
|
BEFREE |
Carriage of IL28B rs12979860 CC genotype was associated with an increased risk for developing liver cirrhosis among patients with HBV infection (CC vs CT + TT: OR = 1.39, 95 % CI = 1.04-1.85).
|
24026885 |
2014 |
|
Hepatitis B
|
|
0.100 |
GeneticVariation
|
BEFREE |
Genetic variation of interleukin-28B (IL-28B) rs12979860 T/C polymorphism is associated with the immune response to interferon (IFN) therapy, which is applied in the treatment of chronic viral hepatitis induced by hepatitis B virus (HBV) and hepatitis C virus (HCV).
|
24874053 |
2014 |
|
Hepatitis B
|
|
0.100 |
GeneticVariation
|
BEFREE |
The IL-28B rs12979860 CC genotype was associated with lower treatment success [odds ratio (OR), 0.31; p = 0.025 and OR, 0.37; p = 0.044 for <400 IU/ml HBV DNA with <40 IU/l ALT, and <2,000 IU/ml HBV DNA with <40 IU/l ALT, respectively].
|
24924923 |
2014 |
|
Hepatitis B
|
|
0.100 |
GeneticVariation
|
BEFREE |
In recipients carrying rs12979860 IL-28B C/C genotype the use of cyclosporine seems to contribute to enhance the probability of developing biliary complications which in hepatitis B and C positives appear to reduce patient survival.
|
25219480 |
2014 |
|
Hepatitis B
|
|
0.100 |
GeneticVariation
|
BEFREE |
Frequency of interleukin 28B rs12979860 C>T variants in Filipino patients chronically infected with hepatitis B virus.
|
25391769 |
2015 |
|
Hepatitis B
|
|
0.100 |
GeneticVariation
|
BEFREE |
IL28B genetic variations (rs12979860) were genotyped by pyrosequencing of DNA samples from 137 individuals with chronic HBV infection [50 inactive carriers (IC), 34 chronic hepatitis B (CHB), 27 cirrhosis, 26 hepatocellular carcinoma (HCC)], and 19 healthy controls.
|
25837166 |
2015 |
|
Hepatitis B
|
|
0.100 |
GeneticVariation
|
BEFREE |
Several association studies with small sample sizes of two SNPs in IL28BB (rs12979860 and rs8099917) showed inconsistent results, so in this study, we aim to evaluate the association between the two SNPs and infection susceptibility of Hepatitis B Virus (HBV) in Asian population, especially in Chinese population by meta-analysis.
|
25962810 |
2015 |
|
Hepatitis B
|
|
0.100 |
GeneticVariation
|
BEFREE |
IL28B rs12979860 TT carriers had an increased risk of death compared with CC+CT carriers (log‑rank test, P = 0.02; HR, 1.62; 95% CI, 1.09-2.42; P = 0.02) only when they were negative for hepatitis B virus (HBV) or hepatitis C virus (HCV) infection.
|
26039912 |
2015 |
|
Hepatitis B
|
|
0.100 |
GeneticVariation
|
BEFREE |
Effect of interferon λ3 gene polymorphisms, rs8099917 and rs12979860, on response to hepatitis B virus vaccination and hepatitis B or C virus infections among hemodialysis patients.
|
26658164 |
2015 |