rs12979860, IFNL4

N. diseases: 84
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Hepatitis
CUI: C0019158
Disease: Hepatitis
0.040 GeneticVariation BEFREE The two proposed functional variants (rs368234815 and rs4803217) were not superior to the discovery SNP rs12979860 with respect to liver inflammation or fibrosis phenotype. 28394349 2017
Hepatitis
CUI: C0019158
Disease: Hepatitis
0.040 GeneticVariation BEFREE In conclusion, the IL28B rs12979860 polymorphism is not associated with fibrosis and liver inflammation in Egyptian HCV G4. 23981065 2014
Hepatitis
CUI: C0019158
Disease: Hepatitis
0.040 GeneticVariation BEFREE In the overall analysis, the IL-28B rs12979860 T/C polymorphism was identified as a genetic risk factor for hepatitis virus-related HCC and LC development. 24085431 2013
Hepatitis
CUI: C0019158
Disease: Hepatitis
0.040 GeneticVariation BEFREE The IL28B rs12979860 CC genotype is associated with a higher prevalence of cirrhosis in HIV-HCV-coinfected patients than CT/TT genotypes, suggesting that IL28B CC carriers may experience a more rapid progression of HCV-related liver fibrosis, perhaps as result of increased liver inflammation. 21592993 2011