rs13181, KLC3;ERCC2

N. diseases: 134
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.090 GeneticVariation BEFREE However, we did not find any association of polymorphism of XRCC1 Arg399Gln (OR = 1.56; 95% CI: 0.32-7.82) and XPD Lys751Gln (OR = 0.46; CI: 0.10-2.19) with GC risk in the study population. 30225185 2018
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.090 GeneticVariation BEFREE However, we found no association between ERCC1 rs11615, ERCC2 rs13181, and ERCC2 rs1799793 and overall survival of gastric cancer. 27173253 2016
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.090 GeneticVariation BEFREE We conducted a prospective study to analyze whether ERCC1 rs11615 and rs3212986 and ERCC2 rs13181 and rs1799793 gene polymorphisms could serve as potential biomarkers for the prognosis of gastric cancer. 26823845 2015
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.090 GeneticVariation BEFREE We investigated three genotypes of XPD, at promoter -114 (rs3810366), and codon 312 (rs1799793), 751 (rs13181), and their associated with gastric cancer susceptibility in a Taiwanese population. 26254397 2015
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.090 GeneticVariation BEFREE In conclusion, our finding suggests that ERCC1 rs3212986 and ERCC2 rs13181 gene polymorphism could influence the response to chemotherapy and clinical outcome of gastric cancer. 26191265 2015
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.090 GeneticVariation BEFREE This meta-analysis aimed to obtain a comprehensive and reliable assessment of the relationships between XRCC1 Arg399Gln and XPD Lys751Gln polymorphisms and the clinical outcomes of gastric cancer (GC) patients treated with oxaliplatin-based chemotherapy. 24590266 2014
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.090 GeneticVariation BEFREE We conclude that ERCC2 rs13181 polymorphism could play different roles in the overall survival of gastric cancer. 23680703 2013
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.090 GeneticVariation BEFREE A statistically significant finding could be seen in noncardia-type gastric cancer for XPD Lys751Gln polymorphism. 23028453 2012
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.090 GeneticVariation BEFREE This meta-analysis concluded that both ERCC2 Lys751Gln and Asp312Asn polymorphisms might contribute to increased risk of GC among Asians. 20981556 2011