rs13181, KLC3;ERCC2

N. diseases: 134
Disease: Skin carcinoma ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Skin carcinoma
CUI: C0699893
Disease: Skin carcinoma
0.030 GeneticVariation BEFREE On stratified analysis by tumor type, XPD Lys751Gln polymorphism was not associated with increased risk of non-melanoma skin cancer, but was significantly related with increased risk of cutaneous melanoma (Gln/Gln vs Lys/Lys: OR=1.15, 95%CI=1.02-1.29, p=0.023; dominant model: OR=1.09, 95%CI=1.01-1.18, p=0.036). 25169498 2014
Skin carcinoma
CUI: C0699893
Disease: Skin carcinoma
0.030 GeneticVariation BEFREE Our findings indicate a reduced NMSC risk in relation to XPD Asp312Asn and Lys751Gln variants. 17687452 2007
Skin carcinoma
CUI: C0699893
Disease: Skin carcinoma
0.030 GeneticVariation BEFREE To test this hypothesis, a cohort study was conducted to examine the association between XPD Lys751Gln polymorphism and risk of a second primary cancer in individuals with NMSC. 15298945 2004