rs13181, KLC3;ERCC2

N. diseases: 134
Disease: Head and Neck Carcinoma ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Head and Neck Carcinoma
CUI: C3887461
Disease: Head and Neck Carcinoma
0.040 GeneticVariation BEFREE However, no statistically significant association was observed between the risk of developing HNC and the ERCC2 Lys751Gln and ERCC3 A>G polymorphisms. 24020925 2014
Head and Neck Carcinoma
CUI: C3887461
Disease: Head and Neck Carcinoma
0.040 GeneticVariation BEFREE There is overall lack of association between XPD Lys751Gln polymorphism and HNC risk under all five genetic models and still no significant association was found in the subgroup analysis by ethnicity and source of controls. 24443924 2014
Head and Neck Carcinoma
CUI: C3887461
Disease: Head and Neck Carcinoma
0.040 GeneticVariation BEFREE In the present study we investigated the association between three polymorphisms of the MUTYH (Tyr165Cys, rs34612342), the OGG1 (Ser326Cys, rs1052133) and the XPD (Lys751Gln, rs13181) genes with head and neck cancer risk. 20571908 2011
Head and Neck Carcinoma
CUI: C3887461
Disease: Head and Neck Carcinoma
0.040 GeneticVariation BEFREE In conclusion, our meta-analysis demonstrated that XPD Lys751Gln polymorphism could be a prediction marker for risk of head and neck cancer. 22179996 2011