Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE ANRIL polymorphisms (rs1333049 and rs3217992) in relation to plasma CRP levels among in-patients with CHD. 31770616 2020
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE Gender-based subgroup tests showed that four polymorphisms (rs75227345, rs2383205, rs10738606 and rs1333049) were associated with CHD in males (p < .05). 31496134 2019
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE Association Study Between Coronary Artery Disease and rs1333049 Polymorphism at 9p21.3 Locus in Italian Population. 28639227 2017
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE Our study aims to explore the association of rs7025486 single-nucleotide polymorphisms (SNP) in DAB2IP and rs1333049 on chromosome 9p21.3 with the coronary artery disease in Chinese population. 28962556 2017
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation GWASCAT Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases. 27790247 2016
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE Despite excellent power, the 9p21 locus SNP (rs1333049) was only modestly associated with MI (HR = 1.09, p-value = 0.02) and marginally with CHD (HR = 1.06, p-value = 0.08). 26950853 2016
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE The leading coronary artery disease-associated SNP rs1333049 was associated with coronary artery disease; however, none of the 9p21 SNP evaluated in the present study were associated with extreme longevity. 25257646 2015
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE This study confirms the association between 9p21 (rs1333049) and fatal CHD in a Norwegian population-based cohort. 24728607 2014
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE Our case-control study and meta-analysis suggest that rs1333049 is a useful risk marker of CHD. 24930384 2014
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation GWASCAT Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. 24262325 2014
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation GWASDB A genome-wide association study of a coronary artery disease risk variant. 23364394 2013
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation GWASDB A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex. 22319020 2012
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE To address the relationship of rs1333049, the 9p21 variant showing the strongest association with coronary heart disease (CHD), with carotid plaques and plaque-free common carotid artery intima-media thickness (CCA-IMT) in older adults from 2 French population-based cohorts. 22436605 2012
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE The Ch9p21 SNPs rs1333049 (OR 1.17; 95% confidence limits 1.11-1.24) and rs10757274 (OR 1.17; 1.09-1.26), MIA3 rs17465637 (OR 1.10; 1.04-1.15), Ch2q36 rs2943634 (OR 1.08; 1.03-1.14), APC rs383830 (OR 1.10; 1.02, 1.18), MTHFD1L rs6922269 (OR 1.10; 1.03, 1.16), CXCL12 rs501120 (OR 1.12; 1.04, 1.20), and SMAD3 rs17228212 (OR 1.11; 1.05, 1.17) were all associated with CHD risk, but not with the CHD biomarkers and risk factors measured. 21804106 2012
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation GWASDB Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease. 22751097 2012
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation GWASDB Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. 21347282 2011
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation GWASCAT A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. 21606135 2011
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation GWASDB Two-marker association tests yield new disease associations for coronary artery disease and hypertension. 21626137 2011
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE Independent association of the variant rs1333049 at the 9p21 locus and coronary heart disease. 21874923 2011
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation GWASDB Large-scale gene-centric analysis identifies novel variants for coronary artery disease. 21966275 2011
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation GWASDB A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. 21606135 2011
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE Recent genetic studies identified the rs1333049 variant on chromosome 9p21 as a major susceptibility locus for coronary artery disease and myocardial infarction (MI). 20231156 2010
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE The results showed that 3 SNPs in whites (rs599839, rs1333049, and rs501120; HRRs were 1.10 (P = 0.044), 1.14 (P < 0.001), and 1.14 (P = 0.030), respectively) and 1 SNP in African Americans (rs7250581; HRR = 1.60, P = 0.05) were significantly associated with incident CHD. 19955471 2010
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE However, the effect of rs1333049 on clinical outcomes in patients with established coronary disease has yet to be determined. 20400779 2010
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.900 GeneticVariation BEFREE We genotyped the rs1333049 single-nucleotide polymorphism in 593 Caucasian individuals with stable coronary artery disease recruited in the Heart and Soul Study. 19171343 2009