rs1360485, HMGB1

N. diseases: 16
Disease: Malignant neoplasm of lung ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Malignant neoplasm of lung
CUI: C0242379
Disease: Malignant neoplasm of lung
0.020 GeneticVariation BEFREE For rs1360485 polymorphism, AG and GG genotypes could decrease the risk of lung adenocarcinoma and female lung cancer by 0.771-fold and 0.789-fold. 29617336 2018
Malignant neoplasm of lung
CUI: C0242379
Disease: Malignant neoplasm of lung
0.020 GeneticVariation BEFREE We found that the CT or CC+CT heterozygotes of the <i>HMGB1</i> rs1045411 polymorphism reduced the risks for lung cancer, while the G/T/C haplotypes of three <i>HMGB1</i> SNPs (rs1360485, rs1045411 and rs2249825) also reduced the risk for lung cancer by almost half (0.486-fold). 29104475 2017