rs1405999227, EGFR

N. diseases: 3
Disease: Progressive cGVHD ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Progressive cGVHD
CUI: C3539781
Disease: Progressive cGVHD
0.010 GeneticVariation BEFREE Regarding the efficacy of anti-EGFR therapy, the patient with an I326V mutation had progressive disease (+115%) despite no genetic alterations detected in the EGFR pathway that could drive resistance, suggesting an alternate resistance mechanism. 30463788 2018